Introduction

Are you looking for the best L-Lysine supplement in USA? Know that you have come to the right place. Now, let us first know;

What is Lysine?

Lysine is an essential amino acid involved in several human functions, including muscle maintenance, sore throat, diabetes, and many more. In addition, Lysine can enhance the performance of an athlete.  

Our body does not produce Lysine on its own. It is essential to consume enough of it through food. While most people who eat a well-balanced diet will get enough Lysine without supplementation, those who have particular dietary limitations may benefit from it. So;

  • What is lysine-rich food?
  • Can you take an L-lysine supplement?
  • What are the benefits of L-lysine supplements?

To answer all such questions and help you find the right supplement for you, we have compiled a list of the top 4 best L-Lysine supplements in USA and included the same in this article. Check it out!

L-Lysine Supplements in USA

Our pick of the 4 best l-lysine supplement of 2024 in USA

Let's take a deep dive into these 4 best L-Lysine Supplements in USA

Best Overall L-Lysine Supplements in USA

Pharmavite

A+

Zotezo review

Nature Made L-Lysine 1000 mg provides a convenient 60-day supply of dietary supplement supporting protein synthesis with each tablet containing 1000 mg of L-Lysine. However, some users may find the large tablet size challenging to swallow and suggest improvements in the packaging for easier handling.

Product details

  • 1000 mg L-Lysine per tablet

  • 60 tablets per bottle

  • 60-day supply

  • Protein synthesis support

  • Dietary supplement

Benefits of Nature Made L-Lysine 1000 mg Tab...

  • 1000 mg L-Lysine per tablet

  • 60 tablets per bottle

  • 60-day supply

  • Protein synthesis support

Drawbacks

  • Large size may be difficult for some to swallow

  • Packaging could be improved for easier handling

NOW Sports - Nutrition and Wellness

A+

Zotezo review

The NOW Supplements L-Lysine 500 mg tablets provide essential support for the immune system, healthy connective tissue, and calcium absorption. While some users may not experience significant benefits, the convenient 250 tablets offer a practical way to incorporate this essential amino acid into one’s daily routine.

Product details

  • Essential amino acid

  • Supports healthy connective tissue

  • Aids in calcium absorption

  • Convenient 250 tablets

  • Contains 500 mg of L-Lysine Hydrochloride

Benefits of NOW L-Lysine 500mg Amino Acid Ta...

  • Supports immune system

  • Essential amino acid

  • Convenient 250 tablets

  • Aids in calcium absorption

Weaknesses

  • Some users may not see significant benefits

  • Limited quantity in each pack

A

Zotezo review

Pure Encapsulations L-Lysine is a high-quality essential amino acid supplement that supports immune function and promotes gum and lip health. Despite being in capsule form, it is easy to swallow and offers long-lasting value, making it a good choice for those seeking immune support at a reasonable price.

Product details

  • Essential amino acid

  • Supports body's natural defenses

  • Nutritional support for immune function

  • Promotes gum and lip health

Benefits of Pure Encapsulations L-Lysine Sup...

  • Easy to swallow capsules

  • Long-lasting jar

  • Supports immune system

  • Good quality at a reasonable price

Disadvantages

  • Not suitable for those who prefer gel tabs

  • Some may find the capsules less convenient than other forms

A

Zotezo review

The L-Lysine 1000mg by Horbaach is a trusted brand offering a vegetarian, non-GMO, and gluten-free formula, although some users may find the caplets too large for easy swallowing, and limited flavor options may not appeal to all consumers.

Product details

  • L-Lysine 1000mg per serving

  • 100 Coated Caplets

  • Free Form Dietary Supplement

  • Vegetarian formula

  • Non-GMO

  • Gluten-free

Benefits of Horbaach L-Lysine 1000mg Caplets

  • Trusted brand

  • Vegetarian formula

  • Non-GMO

  • Gluten-free

Negatives

  • Some users may find the caplets to be too large for easy swallowing

  • Limited flavor options may not appeal to all consumers

Tips for choosing the right l-lysine supplement for you

It is essential to pay attention to each feature of a product. Consider talking to your doctor first before buying the best l-lysine supplement in USA and including it in your routine. Taking the following factors into consideration is a must when investing in a L-lysine supplement.

Form

L-lysine supplements are available in powder and capsules form. It is your preference to choose whichever you like. But, powders allow consumers to quantify the amount of Lysine in each serving more precisely. They are also often less expensive on a per-serving basis. On the other hand, capsules may be more handy for some because they require less time to ingest and are easier to carry.

If you are looking for a Lysine supplement, deciding whether you like a powder or a capsule first will help you narrow down your possibilities. You first have to make a choice.

Certified

Male sure your supplement is third-party verified. Supplements that have been third-party tested are sent to a lab for testing to ensure that they contain what they claim and do not contain high-risk, common contaminants. ConsumerLabs, NSF, and USP are three third-party certifications you can trust.

Dosage

It is a good idea to talk to a doctor about how much Lysine you should include in your diet. Pay attention to the portion size on each packet, as it can range from 500 to 1500 mg per serving. Understand the price and quantity ratio by looking at the above list of top 4 best l-lysine supplements in USA.

Ingredient list

Some Lysine producers include additional components in their formulas, which may influence your purchasing decision if they meet a need you have. Vitamin C, for example, is frequently combined with Lysine. It is wise to buy such a combination product that boosts your immune system. Check the ingredient list and ensure whether you are allergic to any specific ingredients.

Expiry date 

Check the supplement’s expiration date and make sure it has a long shelf life. The shelf life should be up to 18 months from the date of manufacturing. Do not buy supplements that are going to expire soon.

Packaging

If you are buying a powder-form of L-lysine supplement, check the packaging. It should be sealed-packed. There should be no holes or already open portions in the pack. Immediately return the product. Do not use such a product.

Products listed here are carefully reviewed and tested by our expert authors and reviewers. If you buy through links on this page, we may earn a small commission. Here’s our editorial process.

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Benefits of using l-lysine supplement

Taking the best L-Lysine supplements in USA has several advantages. Here are some of the significant benefits you can gain if you keep using the best-quality supplement.

Healing wounds 

One advantage of L-lysine is that it can help wounds heal faster. Lysine is necessary for the synthesis of collagen, a protein that gives our skin and bones much-needed structure and support. Lysine, in particular, functions as a binding agent, assisting in the formation of new cells and stimulating the development of new blood cells.

Protection against cold sore

The Best L-lysine supplements in USA can relieve cold sores. L-lysine acts by stopping HSV-1, the virus that causes cold sores, from spreading throughout our bodies. It also inhibits other cold sore catalysts, such as arginine, which HSV-1 requires to multiply.

Better absorption of calcium

We are aware of the health benefits of calcium. It helps the heart, muscles, and nerves function efficiently. In addition, it strengthens our teeth and bones. L-lysine helps our systems hold on to calcium by enhancing its absorption in the gut and assisting our kidneys in doing so. 

Prevent osteoporosis

Because lysine aids in calcium absorption, the amount of calcium lost in urine reduces. As a result, calcium absorption may help prevent osteoporosis-related bone loss.

Vital growth 

Lysine produces carnitine, a vitamin responsible for converting fatty acids into energy. Carnitine delivers long-chain fatty acids into mitochondria for energy production and carries the toxins produced outside the cells.

Reduce Blood pressure

In a study of 50 persons with lysine insufficiency and high blood pressure, lysine supplements can decrease blood pressure.

Relieve stress

According to studies, eating wheat with extra lysine lowers stress and anxiety. In addition, lysine may help lower cortisol levels in women. In combination with medicines, it regulates schizophrenia symptoms.

Other benefits 

Some other benefits of taking the best L-Lysine supplements in USA are;

  • promoting the healthy growth of skin
  • Treating shingles
  • preventing plaque buildup in arteries
  • supporting hair growth
  • building muscle in bodybuilders
  • helping athletes recover from intense workouts
  • Helps in diabetes management

Side-effects of using L-Lysine Supplements

Taking the best L-Lysine supplement in USA is safe as it rarely shows any side effects. But exceeding the recommended dosage might have some symptoms of;

Do consult your physician if you feel any such symptoms after taking an L-lysine supplement.

There has also been one incidence of kidney illness associated with lysine supplements. Thus, people with kidney or liver problems should proceed with caution and seek medical advice before using a lysine supplement.

There is a probable link between lysine supplements and higher cholesterol. So, people who take the best L-lysine supplement in USA  should regularly check their cholesterol levels.

There is no proper study on whether pregnant or breastfeeding women can take L-lysine supplements. Avoid taking it at the time of pregnancy and post-pregnancy.

While L-lysine is beneficial to people with various conditions, there is evidence that it can raise HIV patients’ viral load. As a result, people with HIV/AIDS should avoid using L-lysine supplements and only eat foods high in lysine (which probably do not produce the same results).

The most effective way to absorb this vitamin, improve amino acid levels, and gain those L-lysine benefits is to eat meals high in lysine.

Experts believe that taking lysine with water on an empty stomach is the most beneficial.

Researchers estimate that a person weighing 70 kilograms (kg) needs 800–3,000 mg of lysine per day. The following factors influence how much a person requires:

  • 12 milligrams per kilogram of body weight for adults.
  • 44 mg/kg for youngsters aged 11 to 12 years
  • 97 mg/kg for babies aged 3 to 6 months old

Before adding the best l-lysine supplement in USA to your diet, you should always consult your doctor.

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Conclusion

Lysine is an essential amino acid that can help with everything from cold sore prevention to anxiety reduction and wound healing. Therefore, everyone should include lysine in their diet. You can do the same and for which you need to eat a lysine-rich food or take the best l-lysine supplement in USA on a daily basis.

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Dr. Heather Smith

MD, FRCP

Medical Practitioner verified

By day I’m a critical care physician and medical leader. By night I’m the mom of 2 chaotic, wonderful boys. Somewhere in the middle of all that, I’m building a skincare brand and trying to save the world from plastic waste.