Introduction

Alpha-ketoglutarate (AKG) is an amino acid supplement that has been steadily gaining popularity among health and fitness enthusiasts over the last few years. Whether you’re looking to build muscle, increase strength and stamina, or support general wellness, taking an AKG supplement can be a great way to start! In this blog post, we’ll delve into the best Alpha-ketoglutarate supplements, the potential benefits of it as a dietary supplement, and provide some tips on choosing the best product for you. Keep reading to discover why adding this super molecule to your diet could help bring powerhouse performance results.

Alpha-Ketoglutarate Supplements in USA

Our pick of the 6 best Alpha-Ketoglutarate of 2024 in USA

Let's take a deep dive into these 6 best Alpha-Ketoglutarate Supplements in USA

Best Overall Alpha-Ketoglutarate Supplements in USA

AJAXERRUE

A+

Zotezo review

The Liposomal Calcium AKG Supplement offers a high absorption rate and is more effective than AAKG, providing support for longevity, age defense, cellular energy, and metabolic function. With its easy-to-swallow soft gel tabs, high bioavailability, and cost-effective pricing, this product is a convenient option for those looking to boost their overall health and well-being. However, elderly individuals may find the capsules too large to swallow comfortably, and some users may be uncertain about the pricing per bottle.

Product details

  • Liposomal Calcium AKG formula

  • High Absorption rate

  • More effective than AAKG

  • Longevity support

  • Age defense properties

  • Enhances cellular energy and metabolic function

Benefits of Calcium AKG Supplement for Longe...

  • High bioavailability due to liposomes

  • Supports energy production and metabolic function

  • Easy to swallow soft gel tabs

  • Can be taken with morning coffee

  • Cost-effective option for quality product

Drawbacks

  • Capsules may be too large for elderly individuals to swallow easily

  • Some users may find the price per bottle to be uncertain

A+

Zotezo review

The Toniiq 1800mg Ultra High Purity Ca AKG Supplement is a highly purified and bioavailable formula that helps maintain energy levels, supports bone strength, and promotes longevity. With its 99%+ purified Calcium Alpha-Ketoglutarate, this supplement is a valuable addition to any wellness routine.

Product details

  • 1800mg Ultra High Purity Ca AKG Formula

  • 99%+ Highly Purified Calcium Alpha-Ketoglutarate

  • Longevity Supplement with Calcium AKG

  • 120 Vegetarian Capsules

Benefits of Toniiq 1800mg Ca AKG Supplement

  • Helps maintain energy levels

  • Highly purified and bioavailable formula

  • Supports bone strength

A+

Zotezo review

The AAKG Powder by Horbaach offers a high-potency formula with 3,000 mg of AAKG per serving, providing increased energy levels and potential cardiovascular health benefits. However, the strong effects may not be suitable for everyone, and individual responses may vary.

Product details

  • AAKG Powder

  • High potency formula with 3,000 mg of AAKG per serving

  • Enjoyable in favorite beverages

  • Expertly crafted formula

Benefits of Horbaach AAKG Powder Supplement ...

  • Increased energy levels

  • Potential cardiovascular health benefits

  • Affordable pricing

  • High potency formula

Disadvantages

  • Potential strong effects may not be suitable for everyone

  • Effects on different individuals may vary

A

Zotezo review

The BULKSUPPLEMENTS.COM AAKG Powder is a pure and clean AAKG supplement that supports blood flow, muscle recovery, and sexual performance. Despite some packaging issues with the zip lock and scooping when the product gets low, it offers potential benefits for those seeking improved physical performance and overall health.

Product details

  • Semi-essential amino acid

  • Pure & clean AAKG powder

  • Building block for other amino acids and nitric oxide

  • Unflavored & gluten-free

Benefits of BulkSupplements AAKG Powder R...

  • Enhanced blood flow

  • Increased sexual desire

  • Improved sexual performance

  • Potential for heightened orgasms

  • Supports muscle recovery and growth

Negatives

  • Uncooperative zip lock on packaging

  • Messy scooping when product gets low

C+

Zotezo review

The Piping Rock AAKG Supplement offers a premium grade, high dosage of 3,600 mg AAKG per serving, making it suitable for athletes and bodybuilders. However, some users may find the large caplets difficult to swallow and may experience minor digestive discomfort after taking the supplement.

Product details

  • 3,600 mg AAKG per serving

  • Premium Grade

  • Athlete and Bodybuilder Formula

  • Non-GMO and Gluten Free

  • Laboratory Tested, using Trusted Ingredients

Benefits of Piping Rock AAKG Supplement R...

  • High AAKG dosage

  • Premium quality

  • Suitable for athletes and bodybuilders

Cons

  • Large caplets may be difficult to swallow for some users

  • Some users reported minor digestive discomfort after taking the supplement

C+

Zotezo review

The Jarrow Formulas Arginine 1000 mg tablets offer great value for men’s health by supporting protein synthesis, nitric oxide production, and tissue repair. While enhancing energy levels and blood pressure, some users may find the tablets disintegrate easily during travel and experience an unpleasant taste.

Product details

  • L-Arginine supports protein synthesis

  • Promotes the production of nitric oxide

  • Supports tissue repair

  • Men's health formula

  • 1000 mg of Arginine per tablet

  • Provides up to 100 servings

Benefits of Jarrow Arginine 1000 – Nit...

  • Supports blood pressure

  • Enhances energy levels

  • Value for money

Drawbacks

  • Tablets may disintegrate easily when traveling

  • Some users may experience an unpleasant taste or aftertaste

Tips for choosing the right Alpha-Ketoglutarate for you

Alpha-ketoglutarate (AKG) supplements are typically made from a salt or ester form of alpha-ketoglutaric acid, a naturally occurring compound in the body. It is formed by the oxidation of an amino acid called glutamate. AKG supplements are often made from a combination of ingredients, including the AKG salt or ester form, as well as other nutrients such as vitamins, minerals, amino acids, and herbal extracts.

The most common form of AKG supplements is calcium alpha-ketoglutarate and magnesium alpha-ketoglutarate, which are forms of AKG combined with minerals. Some supplements also include other ingredients, such as vitamin C, B-vitamins, and minerals, such as zinc and magnesium, to support energy metabolism and overall health.

When purchasing an alpha-ketoglutarate (AKG) supplement, there are a few things to consider to ensure you get a high-quality product that meets your needs.

Quality of Ingredients

Look for a supplement that contains pure and high-quality AKG, and avoid products with fillers or artificial ingredients.

Purity

Look for a supplement that has been tested for purity and potency. This can help ensure that the product contains the stated amount of AKG and is free of contaminants.

Dosage

Consider the recommended dosage of AKG per serving and ensure that the product you choose provides the appropriate amount for your needs.

Form

AKG supplements, such as calcium alpha-ketoglutarate, magnesium alpha-ketoglutarate, and others, come in different forms. Choose the form that best fits your needs and preferences.

Brand reputation

Research the brand and read customer reviews to ensure that the company has a good reputation for producing high-quality supplements.

Consult with a healthcare professional

Consult with a healthcare professional before taking any supplement, as AKG supplements may interact with other medications or have side effects that are not known.

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Benefits of using Alpha-Ketoglutarate

Alpha-ketoglutarate (AKG) is a naturally occurring compound in the body and is a salt or ester form of alpha-ketoglutaric acid. It is believed to have several potential benefits when taken as a supplement, but more research is needed to understand its effects fully.

Energy metabolism

AKG is involved in metabolism, specifically the citric acid cycle, which is the process by which the body converts food into energy. It can support energy production and endurance.

Muscle recovery

AKG may help to support muscle recovery after exercise by removing nitrogen waste products from the body, which can cause muscle fatigue.

Immune function

AKG may help to support the immune system by removing harmful toxins from the body, which can cause inflammation and reduce the function of the immune system.

Anti-aging

AKG is an antioxidant and may help to protect cells from damage caused by free radicals, which are molecules that can damage cells and contribute to aging.

Mental clarity

AKG may support mental clarity by promoting healthy brain function and removing toxins that can cause brain fog.

It’s important to note that more research is needed to understand the effects of AKG supplements fully, and the evidence supporting these potential benefits is currently limited.

Benefits of Alpha-ketoglutarate supplements

Side-effects of using Alpha-Ketoglutarate Supplements

As with any supplement, there may be some side effects associated with AKG.

Digestive discomfort

AKG supplements may cause digestive discomforts such as stomach upset, nausea, or diarrhea.

Allergic reactions

Some people may have an allergic reaction to AKG or the other ingredients in the supplement. Signs of an allergic reaction may include skin rash, hives, itching or difficulty breathing.

Interaction with medications

AKG may interact with certain medications, particularly those metabolized by the liver. It’s essential to consult with a healthcare professional before taking any supplement if you are on any medication.

Pregnancy and breastfeeding

There is not enough information about the safety of AKG during pregnancy and breastfeeding, so it’s best to avoid it in these cases.

It’s important to note that AKG supplements have not been thoroughly studied, and more research is needed to understand the potential side effects and interactions with medications fully. 

As always, it’s essential to consult with a healthcare professional before taking any supplement, as they can best advise you on the safety and appropriateness of any supplement for your situation.

The recommended dosage of alpha-ketoglutarate (AKG) supplements can vary depending on the product and the intended use. It’s essential to follow the manufacturer’s recommended dosage instructions and consult with a healthcare professional before taking any supplement.

 

The typical dosage of AKG supplements ranges from 2 to 6 grams per day, taken in divided doses. However, there is limited research to establish the optimal dosage for AKG. Some studies have used doses as high as 12 grams per day, but more research is needed to determine if such high doses are safe or effective.

 

Additionally, individual needs can vary, so it’s essential to consult a healthcare professional before taking any supplement. They can advise on the safety and appropriate dosage for your situation.

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Frequently asked questions on Alpha-Ketoglutarate

1. Is the AKG supplement safe to take long-term?

2. Can AKG supplements be taken with other supplements or medications?

3. Is the AKG supplement suitable for vegetarians or vegans?

4. Can AKG supplements be taken by people with pre-existing medical conditions?

5. Can AKG supplements be taken with caffeine?

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Conclusion

Alpha-ketoglutarate is a crucial player in the Krebs cycle and energy production in cells. It’s also essential for athletes because it can help reduce muscle fatigue. If you’re looking for an edge, alpha-ketoglutarate supplements might be worth considering; make sure to talk to your doctor first. Have you tried alpha-ketoglutarate supplements? Do you think they helped you perform better or recover faster? Let us know in the comments below!

 

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Dr. Heather Smith

MD, FRCP

Medical Practitioner verified

By day I’m a critical care physician and medical leader. By night I’m the mom of 2 chaotic, wonderful boys. Somewhere in the middle of all that, I’m building a skincare brand and trying to save the world from plastic waste.